In response to the COVID-19 health issue, we are offering telehealth as well as in-person appointments. Click to learn more.

Molecular Markers Help Assess Prostate Cancer Risk

September 18, 2014

One of the biggest challenges in diagnosing early stage prostate cancer is properly staging and grading patients to determine the best treatment plan.  Current methods such as clinical staging, PSA serum levels and Gleason scores can help but have limitations. Both patients and physicians need more accurate and objective predictors of recurrence of the disease.

After extensive review, The Urology Group has decided to evaluate two molecular markers on prostate biopsy tissue in certain patient populations. Molecular markers are fragments of DNA that have been identified as indicating certain results in the human body.

Confirm MDx is a molecular marker that helps distinguish patients with a “true” negative biopsy from those still at risk for undetected cancer.  If the Confirm MDx test is negative, the patient has a greater than 90% certainty of not having prostate cancer.  The test results are valid for 24 months, so unless something changes clinically, no repeat biopsy will be needed for two years.  If positive, the patient will have another biopsy and about 50% of those patients will be diagnosed with prostate cancer.

The Confirm MDx test helps keep men without prostate cancer from undergoing unnecessary additional biopsies and identifies high-risk patients who may require repeat biopsies and potential treatment.

Patients with newly diagnosed low-risk prostate cancer–and their physicians–need to know how aggressive the disease is. The second molecular marker, Oncotype DX, helps with that determination. The analysis looks at various pathways to evaluate how quickly the cancer has been growing. The test builds on traditional clinical and pathologic factors to provide additional, clinically relevant insight.

The Oncotype DX assay results provide an individualized risk assessment that can help a patient and his physician make a confident choice between active surveillance (watchful waiting) and immediate treatment.

Together, these two molecular markers may help provide a clearer picture of a patient’s condition and help his health care team make better patient-specific recommendations for his health and well-being.

Recent Featured Blog Posts

  1. It’s All Fun and Games Until Someone Gets a Kidney Stone

    Thirsty? Be sure to say ‘yes’ to that tall glass of water. It may save you from searing pain by the end of the summer. That’s because summer is peak season for kidney stones, hard little formations that develop in the kidneys when urinary minerals and salts crystallize and bind together. Often, stones aren’t even…

    Read More
  2. The Urology Group: Celebrating 25 Years

    In 1996, the medical world was entering a remarkable age of discovery: Dolly the sheep was cloned; a combination therapy treatment was discovered to manage HIV/AIDS; and Pfizer patented a revolutionary erectile dysfunction drug called Viagra. And in that same year, 25 years ago, 23 physicians from seven different urology practices joined to form The…

    Read More
  3. 6 Travel Tips for Those Experiencing OAB

    Here are six tips from Dr. Douglas Feeney for making it to the bathroom on time, whether you’re traveling locally or abroad this summer.

    Read More

Virtual Assistant

Virtual Assistant

How may I assist you today?

I need help with ‘Directions & Hours’
(Please select a location from the list below)
I need help with ‘ Billing Questions’
(Please select an option below)

I need help with ‘Billing Questions’

What number should I call to pay my bill?

If your bill is from The Urology Group, please call (513) 841-7474 to pay your bill.

If your bill is from The Urology Center, please call (513) 841-7475 to pay your bill.

I need help with ‘Making, Rescheduling or Confirming an Appointment’

If you would like us to call you to set up an appointment, please click here to request a call back.

If you would like to call us, please call
513-841-7400
to speak with a representative.
Our hours are:

Monday-Friday: 7:30am – 5:00pm

I need help with ‘Questions About Test Results’

please call us at:

513-841-7400

Our hours are:

Monday-Friday: 7:30am – 5:00pm

I need help with ‘Medication Refills’

please call us at:

513-841-7400

Our hours are:

Monday-Friday: 7:30am – 5:00pm

I need help with ‘Returning a Call from the Office’

please call us at:

513-841-7400

Our hours are:

Monday-Friday: 7:30am – 5:00pm

I need help with ‘A Copy of My Medical Records’

please call us at:

513-841-7400

Our hours are:

Monday-Friday: 7:30am – 5:00pm