XIAFLEX® Treatment for Peyronie’s Disease

The curvature of the penis associated with Peyronie’s disease is caused by a buildup of scar tissue which feels like a bump under the skin of your penis.

1. During your first in-office visit, your urologist will inject XIAFLEX into the scar tissue.
2. A second injection will take place during your second visit, about 1-3 days later.
3. Several days later a member of the urology care team will perform in-office exercises to stretch and straighten your penis.
4. For the next six weeks you will spend a few minutes each day doing these same stretching and straightening exercises at home.

Once this first treatment cycle is complete, your urologist will determine if more treatment cycles are needed. Depending on the severity of your curvature, up to four cycles may be necessary. Treatment cycles are scheduled six weeks apart.

Side Effects and Sexual Activity

Swelling, bruising, and pain near the injection site are possible following each treatment cycle.

Sexual activity must be avoided:

• Between the first and second injections of a treatment cycle
• For at least four weeks after the second injection of each treatment cycle
• Until pain and swelling have gone away

How Successful is XIAFLEX?

• Studies show up to 17% reduction in curvature following XIAFLEX treatment
• XIAFLEX is the only FDA-approved nonsurgical option to treat Peyronie’s disease
• 94% of men pay nothing for XIAFLEX. Learn more.
• XIAFLEX does not affect the length of your penis